Science and Technology : Scientists Can Now Radically Expand the Lifespan of Mice—and Humans May Be Next

Clyde C Coger Jr

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Scientists Can Now Radically Expand the Lifespan of Mice—and Humans May Be Next


With a bit of clever genetic engineering, a team of scientists has just found an astonishing way to significantly expand the natural lifespan of mice. Now, at least one biotech company hopes to translate this breakthrough to fight aging in humans ...


https://www.yahoo.com/autos/scientists-now-radically-expand-lifespan-202537929.html

b4bd4fee4f179f5c6981cb6ebdef7538

Medical researchers at Mayo Clinic have made this decade's biggest breakthrough in understanding the complex world of physical aging

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Naturally occurring p16Ink4a-positive cells shorten healthy lifespan


Abstract
Cellular senescence, a stress-induced irreversible growth arrest often characterized by expression of p16Ink4a (encoded by the Ink4a/Arf locus, also known as Cdkn2a) and a distinctive secretory phenotype, prevents the proliferation of preneoplastic cells and has beneficial roles in tissue remodelling during embryogenesis and wound healing. Senescent cells accumulate in various tissues and organs over time, and have been speculated to have a role in ageing ...


http://www.nature.com/nature/journal/vaop/ncurrent/full/nature16932.html


At a glance

nature16932-f3.jpg


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