Science and Technology : GENETIC LINK TO BREAST CANCER

Discussion in 'Science and Technology' started by Kemetstry, Sep 24, 2012.

  1. Kemetstry

    Kemetstry going above and beyond PREMIUM MEMBER

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    New genetic clues to 4 types of breast cancer found
    By The Associated Press
    [​IMG]
    News about Genetic clues to breast cancer

    bing.com/news

    NEW YORK — Scientists reported Sunday that they have completed a major analysis of the genetics of breast cancer, finding four major classes of the disease. They hope their work will lead to more effective treatments, perhaps with some drugs already in use.

    The new finding offers hints that one type of breast cancer might be vulnerable to drugs that already work against ovarian cancer.
    The study, published online Sunday by the journal Nature, is the latest example of research into the biological details of tumors, rather than focusing primarily on where cancer arises in the body.
    The hope is that such research can reveal cancer's genetic weaknesses for better drug targeting.
    "With this study, we're one giant step closer to understanding the genetic origins of the four major subtypes of breast cancer," Dr. Matthew Ellis of the Washington University School of Medicine said in a statement. He is a co-leader of the research.
    "Now we can investigate which drugs work best for patients based on the genetic profiles of their tumors," he said.
    Video: Study eyes the genetics of breast cancer (on this page)
    The researchers analyzed DNA of breast cancer tumors from 825 patients, looking for abnormalities. Altogether, they reported, breast cancers appear to fall into four main classes when viewed in this way.
    One class showed similarities to ovarian cancers, suggesting it may be driven by similar biological developments.
    "It's clear they are genetically more similar to ovarian tumors than to other breast cancers," Ellis said. "Whether they can be treated the same way is an intriguing possibility that needs to be explored."
    The report is the latest from the Cancer Genome Atlas, a federally funded project that has produced similar analyses for brain, colorectal, lung, and ovarian cancers.


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  2. Kemetstry

    Kemetstry going above and beyond PREMIUM MEMBER

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  3. Fieldpea

    Fieldpea Well-Known Member MEMBER

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    I am in remission for a Stage 1 DCIS breast cancer (diagnosis and lumpectomy in 2010). If all goes well with me, I will wind up officially *free and clear* in the year 2015. So far, so good.


    Anyhow, though my cancer was not triple negative (estrogen positive with mine), in terms of approach to treatment (surgery, radiation, medication), maybe my medical oncologist will have me try something already in existence (associated with some other type of cancer) other than Arimidex--the hormonal med that I take now.


    In the meantime, I'm glad that this advance has happened, and I hope that application of treatments for the triple negatives saves lives.


    LADIES: If you haven't been self-examining yourselves monthly (and you know you should), and/or if you've been putting off doing annual mammograms, then git your act together. This kind of stuff ain't to be played with! I got lucky! Mine was discovered through a routine mammo, and due to its location (near the chest wall), as it happens, there was NO WAY that I was going to find it through self exams, so...


    Come on, now...


    One Love, and PEACE
     
  4. Kemetstry

    Kemetstry going above and beyond PREMIUM MEMBER

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    From your mouth to GODS ears. They are applying a lot of money to the cause now. There are new break thrus all the time. Heres hoping you get a genetic cure in the future






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